Vimentin and Anti Vimentin Antibodies in Chagas' Disease
نویسندگان
چکیده
منابع مشابه
Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin
Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis (RA) and can be detected in approximately 40% of RA sera. The antigen, a doublet of protein bands of about 50 kDa, is present in placenta and in RA synovial tissue. Although it has been stated that the Sa antigen is citrullinated vimentin, experimental proof for this claim has never been published. In this study,...
متن کاملDisease activity and its correlation with anti-mutated citrullinated vimentin antibodies and other factors in rheumatoid arthritis
Objectives: Our aim was to determine the disease activity (DAS28) and its correlation with antiMutated Citrullinated Vimentin antibody (antiMCV) positivity and other factors in Rheumatoid Arthritis (RA) patients, Saudis and non-Saudis. And to compare Disease Activity measurements using ESR (DAS28-ESR) and CRP (DAS28-CRP). Patients and methods: Retrospectively, data were obtained by files’ revie...
متن کاملThe role of antibodies to mutated citrulinated vimentin (anti-MCV) in juvenile idiopathic arthritis patients
Results Positive anti-MCV Ab were detected in only 3/58 (5,2%) JIA patients, and were significantly elevated in two RF positive polyartritis patients, and slightly elevated in 1/19 (5,3%) patients with enthesitis-related arthritis (ErA). Among all patients, anti-CCP Ab were positive only in one anti-MCV positive polyarticular JIA patient. Anti-MCV and RF positivity correlated statistically (r =...
متن کاملVimentin in Bacterial Infections
Despite well-studied bacterial strategies to target actin to subvert the host cell cytoskeleton, thus promoting bacterial survival, replication, and dissemination, relatively little is known about the bacterial interaction with other components of the host cell cytoskeleton, including intermediate filaments (IFs). IFs have not only roles in maintaining the structural integrity of the cell, but ...
متن کاملAntibodies to mutated citrullinated vimentin and disease activity score in early arthritis: a cohort study
INTRODUCTION The aim of our study was to investigate the association between arthritic disease activity and antibodies to mutated citrullinated vimentin (anti-MCV), because such a relation has been suggested. METHODS Anti-MCV levels were measured in 162 patients with early arthritis (123 with rheumatoid arthritis and 39 with undifferentiated arthritis) at baseline and at 1 and 2 years of foll...
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ژورنال
عنوان ژورنال: Arquivos Brasileiros de Cardiologia
سال: 2018
ISSN: 0066-782X
DOI: 10.5935/abc.20180038